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DOV-216,303 Free Base

Glpbio
Catalog No:GC34559-10mM (in 1mL DMSO) CAS No.:66504-40-3 MDLNo: Brand:Glpbio purity: 特性: Purpose:DOV-216,303(FreeBase)是有效的5-羟色胺、去甲肾上腺素、多巴胺再摄取的三重抑制剂,其对hSERT、hNET和hDAT的IC50值分别为14nM,20nM和78nM。在嗅球切除大鼠模型中,可增加前额皮质中单胺的释放及具有抗抑郁的作用。DMSO : ≥ 125 mg/mL (547.96 mM);H2O : < 0.1 mg/mL (insoluble)
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